The Bills attempt to win seven in a row when they host the 49ers in this Week 13 NFL odds, prediction, and pick.

On Tuesday, we reported on Buffalo’s sterling record following bye weeks under Head Coach Sean McDermott, which was quickly ...

The Baltimore Ravens have the NFL's No. 1 offense, so it's fitting QB Lamar Jackson and RB Derrick Henry are No. 1 fantasy options at their positions.

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on “Sunday Night Football” in Week 13. The ...

A disciple of hyper-aggressive deceased Philadelphia Eagles defensive coordinator Jim Johnson, McDermott’s defenses share ...

WR Curtis Samuel (vs. 49ers) — Samuel made mincemeat out of the Chiefs in his last game. But with Keon Coleman and Dalton ...

How much weight do you want to put on the frozen-Fish angle? The forecast at Lambeau is 21 degrees, a real feel of 4 with 15 ...

Simpson carried the ball 29 times against the Lions and set a new NFL record with 273 rushing yards, breaking his own record ...

Daniel Jones reportedly signs with the Vikings. Saquon Barkley enters the MVP conversation, but Lamar Jackson’s case remains ...

San Francisco 49ers defensive end Nick Bosa missed Wednesday's practice as the team began preparations for Sunday's game ...

Bills' QB Josh Allen is the current favorite for MVP. Expectations aren't something I like to make a habit. However, it's ...

While the 49ers look like an easy opponent, San Francisco's health could be a major factor in the game, warns one NFL expert.