Here are the full injury reports for the Buffalo Bills and San Francisco 49ers ahead of their Week 13 matchup at Highmark ...

The Buffalo Bills might have a chance to clinch the AFC East on Sunday night when they battle the injury-decimated San ...

In a season where running backs are thriving in the NFL, the 49ers hope to get Christian McCaffrey back on track.

Former Buffalo Bills defensive end Leonard Floyd spoke about facing his old team on Sunday night with the San Francisco 49ers ...

The Buffalo Bills (9-2) are moving on to their their Week 13 contest against the San Francisco 49ers (5-6). Prior to that, ...

With only a few weeks left on the college football slate, NFL draft season is beginning to hit its stride. Before the San ...

Upon re-joining the Bills, Phillips brought back his long-standing tradition. In the past during practice, Phillips has worn ...

One of the top receivers in the league will be featured when George Kittle and the San Francisco 49ers visit the Buffalo ...

The Buffalo Bills will face the San Francisco 49ers in Week 13. Here’s the latest fantasy football news and advice to help you with your lineups this week and moving forward, especially regarding TE ...

The 49ers have dealt with injuries to key players all season. Brandon Aiyuk injured his knee, Brock Purdy missed last week's ...

You can listen on SiriusXM satellite radio on channel 225 (Bills feed) and channel 226 (49ers feed), and on traditional radio ...

Brock Purdy missed the 49ers' last game against the Packers, but the Bills are preparing as if he's playing on Sunday night.