The San Francisco 49ers placed running back Christian McCaffrey on injured reserve Tuesday a day after coach Kyle Shanahan ...

Many are curious about the 49ers’ injury updates, which put Christian McCaffrey and Jordan Mason on IR. Fans now wonder how ...

The San Francisco 49ers have signed a former New York Jets running back to replace the injured Christian McCaffrey and Jordan ...

The San Francisco 49ers and fantasy football players who were relying on the NFC West team's running backs are probably all ...

The San Francisco 49ers shored up their suddenly thin running back corps on Tuesday by claiming Israel Abanikanda off waivers ...

Former Wisconsin Badgers running back Isaac Guerendo is in line to serve as the San Francisco 49ers starting running back for ...

The 49ers signed two running backs to their practice squad after Christian McCaffrey and Jordan Mason were placed on injured ...

The San Francisco 49ers injury list continues to grow in the second half of the season. Following their Week 13 loss to the ...

The San Francisco 49ers’ 35-10 Week 13 loss to the Buffalo Bills was costly in more ways than one. Not only did it make San ...

The Los Angeles Rams' bitter rival San Francisco 49ers just received news that their All-Pro running back Christian McCaffrey ...

Rookie fourth-round pick Isaac Guerendo seemed to be an afterthought in the San Francisco 49ers backfield with Christian ...