Givens suffered a torn pec in the 49ers’ Week 13 loss to the Buffalo Bills. His injury-riddled season is over after only ...

The San Francisco 49ers are a gigantic mess. Nothing looks right on offense. Injuries have decimated both sides of the ball.

San Francisco 49ers coach Kyle Shanahan is sharing an update on Trent Williams and his family after the left tackle's son was ...

Former Wisconsin Badgers running back Isaac Guerendo is in line to serve as the San Francisco 49ers starting running back for ...

The 49ers brass — Kyle Shanahan, John Lynch, and CEO Jed York chief among them — have not wavered on their commitment to ...

The San Francisco 49ers have signed a former New York Jets running back to replace the injured Christian McCaffrey and Jordan ...

The 49ers opened the practice window for safety Talanoa Hufanga, who has missed the last seven games with a wrist injury.

Williams’ wife, Sondra, announced on Instagram on Sunday, Dec. 1 that their son Trenton O'Brien Williams Jr. was stillborn on ...

The San Francisco 49ers' season has been on the brink for weeks, and the Week 13 blowout loss to the Buffalo Bills certainly ...

NFL Week 14 odds, picks, predictions, TV channel, streaming information for Sunday football game between Chicago Bears and ...

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

This is the live blog for the 49ers' Week 13 road game against the Buffalo Bills. This will be updated frequently with ...